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. pixlr-o-matic. 2019-12-11.Bapineuzumab for the treatment of Alzheimer’s disease in patients with mild-to-moderate dementia: is it worthwhile?
Bapineuzumab (IONIS®) is an acetylcholinesterase inhibitor, developed for the treatment of Alzheimer’s disease (AD), that targets brain soluble ?-amyloid peptide. A phase 2 trial of bapineuzumab in AD patients with mild-to-moderate dementia is underway. This review will describe the rationale for the development of bapineuzumab, a summary of the clinical data from the published phase 1 and 2 trials and the criteria needed to progress bapineuzumab towards a phase 3 trial. The principal adverse event seen in the phase 2 bapineuzumab trial was injection-site reaction. The Bapineuzumab-Investigating New Dementia (BIND) trial is expected to provide the final data needed for the FDA to approve bapineuzumab for the treatment of AD patients with mild-to-moderate dementia.Q:
Why does this for loop iterate twice?
Suppose I have:
for(i = 0; i “In the beginning, there was chaos.” “It was in the beginning of time that the first man and the first woman came together and knew that they were meant to be together.” “And they cried.” “But then they dried their eyes and got down to the business at hand.” “And started to prepare the first heart.” “But first they had to make them heart-shaped.” “The rest, as they say, is history.” “Man and woman were blessed to have two hearts.” “But that was
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